Avtor/Urednik     Poredoš, P
Naslov     Intima-media thickness and cardiovascular disease
Tip     članek
Vir     In: Belch JJF, editor. EUROCHAP. Proceedings of the 16th European chapter congress of the International union of angiology; 2005 Oct 25-27; Glasgow. Bologna: Medimond,
Leto izdaje     2005
Obseg     str. 25-30
Jezik     eng
Abstrakt     Population studies have shown a strong correlation between carotid IMT and several cardiovascular risk factors and it has also been found to be associated with the extent of atherosclerosis and end-organ damage of high risk patients. Therefore, increased carotid IMT is a mirror of atheroscleroric burden and predictor of subsequent events. Because of its quantitative value, carotid IMT measurement is more and mare frequently used in clinical trials to test the effects of different preventive measures, including drugs. More recently, there has been interest in the clinical use of this technique for detecting preclinical (asymptomatic) atherosclerosis and for identifying subjects at high risk. Measurement of carotid IMT could influence a clinician to intervene with medication and to use more aggressive treatment of risk factors in primary prevention, and in patients with atherosclerotic disease in whom there is evidence of progression and extension of atherosclerotic disease. For more extensive use of this method in clinical practice a consensus concerning the standardization of methods of measurement and precise definition of threshold between normal and pathologic IMT value is urgently needed.
Deskriptorji     CAROTID ARTERIES
TUNICA INTIMA
TUNICA MEDIA
ATHEROSCLEROSIS
INSULIN RESISTANCE
RISK FACTORS
HYPERTENSION
CORONARY DISEASE