Avtor/Urednik     Potočnik, Marko; Kocjan, Boštjan; Seme, Katja; Luzar, Boštjan; Babič, Dunja Z; Poljak, Mario
Naslov     Beta-papillomaviruses in anogenital hairs plucked from healthy individuals
Tip     članek
Vir     J Med Virol
Vol. in št.     Letnik 78, št. 12
Leto izdaje     2006
Obseg     str. 1673-8
Jezik     eng
Abstrakt     A total of 150 specimens of anogenital hairs plucked from the scrotal, pubic, and perianal region of 51 immunocompetent healthy male individuals were tested for the presence of beta-papillomaviruses (beta-HPV) using the nested M(a)/H(a) polymerase chain reaction. Beta-HPV were found in a total of 38 (25.3%) of 150 hair samples. According to the sampling sites, beta-HPV were detected in 18/51 (35.3%), 13/50 (26.0%), and 7/49 (14.3%) plucked hair samples obtained from the pubic, scrotal, and perianal region, respectively. The prevalence of beta-HPV in the plucked pubic hairs was significantly higher than in the perianal hairs (P = 0.013). In contrast, the difference in the prevalence of beta-HPV in the pubic and scrotal hairs as well as in scrotal and perianal hairs did not reach statistical significance (P = 0.302 and P = 0.227, respectively). The difference in the lifetime-cumulative sun exposure is the most likely explanation for the differences obtained on beta-HPV prevalence. Beta-HPV genotype HPV-38 was detected most frequently, followed by HPV-36, HPV-15, and HPV-14D. In addition to the beta-HPV recognized officially five partial DNA sequences suggesting putative new HPV genotypes were identified.
Deskriptorji     IMMUNOCOMPETENCE
ADULT
DNA, VIRAL
GENOTYPE
HAIR
MOLECULAR SEQUENCE DATA
PHYLOGENY
PREVALENCE
PUBIC SYMPHYSIS
SCROTUM
SEQUENCE ANALYSIS, DNA