Avtor/Urednik		Vujasinović, Miroslav; Tepeš, Bojan
Naslov		Nealkoholna zamaščenost jeter
Prevedeni naslov		Nonalcoholic fatty liver disease
Tip		članek
Vir		Gastroenterolog
Vol. in št.		Letnik 10, št. 22
Leto izdaje		2006
Obseg		str. 41-7
Jezik		slo
Abstrakt		Nonalcoholic fatty liver disease is a clinicopathological entity characterized by histological spectrum that ranges from steatosis to steatohepatitis, fibrosis and cirrhosis. It is highly recognized condition and is considered the hepatic manifestation of the metabolic syndrome. It is commonly characterized by elevated plasma liver enzyme levels and is more common in obese, diabetic and hyperlipemic patients. Liver biopsy is the gold standard for diagnosis. Prognosis is generally good, but occasionally cirrhosis and liver failure developed. No specific pharmacological treatment is available at the moment. Nonalcoholic fatty liver disease will probably become the most frequent liver ailment in the next decades.
Izvleček		Nealkoholna zamaščenost jeter je kliničnopatološki sindrom s širokim spektrom histološliih sprememb, od steatoze do steatohepatitisa, fibroze in ciroze. Gre za pogosto bolezen, ki je jetrna komponenta metaboličnega sindroma. Zanj so značilne povišane vrednosti transaminaz in je pogostejša pri bolnikih z diabetesom in hiperlipidemijo. Za diagnozo je odločilnega pomena biopsija jeter. Prognoza je načeloma dobra, vendar pri posameznih bolnikih bolezen lahko napreduje do ciroze in jetrne odpovedi. Zaenkrat ni učinkovite farmakološke terapije. Nealkoholna zamaščenost jeter bo v naslednjih desetletjih verjetno postala najpogostejša jetrna boleren.
Deskriptorji		FATTY LIVER LIVER CIRRHOSIS