Avtor/Urednik		Pikelj-Pečnik, Andreja
Naslov		Elektrokardiografske spremembe pri bolnikih z lymsko boreliozo
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje		2006
Obseg		str. 63
Jezik		slo
Abstrakt		Lyme borreliosis, zoonosis, caused by Borrelia burgdorferi sensu lato is endemic to Slovenia and may affect the heart during the early stakes of the disease. Lyme carditis, whose incidence in Europe is estimated at 0.3%-4%, is most frequently shown as symptomatic atrioventricular (AV) conduction disturbances, myocarditis, pericarditis or dilatative cardiomyopathy. There is no data about clinically silent simultaneous affectedness of the heart in the course of other early forms of Lyme borreliosis. We anticipated that the heart is affected also in patients without diagnosis of Lyme carditis, that in the event of a clinical and/or laboratory hematogenous dissemination of the agent, the heart would be affected more frequently than in the localized form of the disease, and that involvement of the heart is reflected in electrocardiographic changes. We included successive, previously healthy patients of both sexes, aged 18-60, suffering from an early Lyme borreliosis, with no clinical diagnosis of Lyme carditis. In the first part of our research we included 474 patients of which 254 had developed an early spread Lyme borreliosis (multiple erythema migrans and early Lyme neuroborreliosis) and 220 a solitary erythema migrans. We performed a standard ECG in these patients and compared ECG records of the two groups. In the second part of our research we included 50 patients of which 20 had developed an early spread of Lyme borreliosis and 30 a solitary erythema migrans. At the time of the diagnosis and during the control check-up two months later, we recorded a five minute high-resolution ECG in standard leads. We analysed the differences between the first and the second ECG recording for each patient. In the first part of our study, the ECG analysis was performed manually and in the second part of the study both automatically (CardioSoft software) and manually. (Abstract truncated at 2000 characters)
Deskriptorji		LYME DISEASE ELECTROCARDIOGRAPHY BORRELIA BURGDORFERI ARRHYTHMIA MYOCARDITIS PERICARDITIS CARDIOMYOPATHY, CONGESTIVE HEART RATE ERYTHEMA CHRONICUM MIGRANS