Avtor/Urednik		Fajdiga, I; Žargi, M; Šmid, L
Naslov		Laser induced autofluorescence in diagnostics of early laryngeal cancer
Tip		članek
Vir		In: Žargi M, editor. Proceedings of the 11th Danube symposium 2006. International otorhinolaryngological congress; 2006 Sep 27-30; Bled. Bologna: Monduzzi editore,
Leto izdaje		2006
Obseg		str. 1-7
Jezik		eng
Abstrakt		Autofluorescence imaging (induced by laser blue light at 442 nm and captured by an image-intensified camera through a laryngeal telescope) was performed in 108 patients with laryngeal pathologies (in 74 of whom malignancy was suspected) and compared to standard microlaryngoscopy. The acquired white-light and fluorescence images of 307 lesion (69 histopathologically malign and 238 benign) were assessed independently as malignant or not malignant and then compared to histopathological findings. The sensitivity of fluorescence was 86.9 % and 71.0 % in white-light observations while their specificity was 82.8 % and 80.6 % respectively. The sensitivity difference was statistically significant (McNemar test). The study showed that autofluorescence imaging is useful complementary method to microlaryngoscopy for detecting and delineating laryngeal malignancies.
Deskriptorji		LARYNGEAL NEOPLASMS LASERS FLUORESCENCE