Avtor/Urednik		Keše, Darja
Naslov		Okužbe z mikoplazmami in klamidijami pri materah in novorojencih
Prevedeni naslov		Chlamydia trachomatis and mycoplasmas infections in mothers and in their newborn infants
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 45, št. Suppl 3
Leto izdaje		2006
Obseg		str. 75-80
Jezik		slo
Abstrakt		Infections with Chlamydia trachomaris, Mycoplasma hominis and Uraplasma spp. in pregnant women may be related to premature labor and to perinatal complications. Laboratory diagnosis of C. trachomatis infection in newborns is made by culture, direct immunofluorescence or by polymerase chain reaction test in conjunctival swabs or respiratory samples. It is important to make an early diagnosis of infection with C. trachomatis because of antibiotic treatment availability, it prevents transmission of bacteria and it prevents sequels of infection. A lot of studies confirm the ability of urogenital mycoplasmas, especially Ureaplasma spp. to cause pneumonia, bacteremia and meningitis in newborns. Culture remains by far the most widely accepted and applied method of ureaplasma isolation, although during the last few years polymerase chain reaction is gaining more attention since it represents a relatively rapid method of ureaplasma detection and allows for earlier initiation of appropriate treatment.
Izvleček		Okužba nosečnice z bakterijami Chlamydia trachomatis, Mycoplasma hominis in z Ureaplasma spp. lahko vpliva na prezgodnji porod in na kasnejše zaplete pri materi in njenem otroku. Klamidijsko okužbo dokazujemo pri novorojencu v brisu očesne veznice in v kužninah iz dihal z direktno imunofiuorescenco, osamitvijo bakterije ali s testom verižne reakcije s polimerazo. Zgodnje odkrivanje okužb z bakterijo C. trachomatis je pomembno, ker omogoča antibiotično zdravljenje, preprečuje širjenje bakterije in dolgotrajne posledice okužbe. Veliko študij je potrdilo vzročno povezavo urogenitalnih mikoplazem, posebno Ureaplasma spp. pri pljučnici, bakteriemiji in meningitisu novorojenca. V laboratorijski diagnostiki urogenitalnih mikoplazem je zaenkrat najpomembnejša metoda osamitev bakterije, čeprav v zadnjem času vse večji pomen zavzema metoda verižne reakcije s polimerazo, ki je relativno hitra, visoko občutljiva in specifična.
Deskriptorji		PREGNANCY COMPLICATIONS, INFECTIOUS INFANT, NEWBORN, DISEASES MYCOPLASMA INFECTIONS CHLAMYDIA INFECTIONS CHLAMYDIA TRACHOMATIS PREGNANCY INFANT, NEWBORN