| Avtor/Urednik | Fister, Miša | |
| Naslov | QT variabilnost pri bolnikih po presaditvi srca | |
| Tip | monografija | |
| Kraj izdaje | Ljubljana | |
| Založnik | Univerza v Ljubljani, Medicinska fakulteta | |
| Leto izdaje | 2006 | |
| Obseg | str. 46 | |
| Jezik | slo | |
| Abstrakt | BACKGROUND. QT interval and QT variability reflect depolarization and repolarization of the myocardial cells. Their increased values are used as risk factors for sudden cardiac death. Autonomic nervous system and electrophysiological properties of the ventricular myocardium influence the QT interval differently under different pathophysiological and physiological circumstances. AIM. By measuring the length and variability of QT interval and ventricular evoked responses (VER) we wanted to determine the effect of autonomic nervous system and electrophysiological properties of the ventricles to the repolarization of myocardial cells in a transplanted heart. HYPOTHESIS. We tested following hypotheses: The length and variability of QT interval in patients after heart transplantation are affected by ventricular electrophysiological properties, and are not affected by autonomic nervous system. METHODS. We involved 9 heart transplant patients in a prospective study. We simultaneously made 3 consecutive 5-minute high resolution 12 lead ECG (HRECG) and VER measurements with the patients 1) having intrinsic heart rate, 2)having paced heart rate, 3) having the heart paced from the opposite electrode. To determine the influence of ventricular electrophysiological properties we used the length of paced QT interval and VER measurement, whereas to determine the influence of autonomic nervous system we used the markers of heart rate variability. We analyzed digitalized HRECG data by using ECG Segment Analyzer, and VER measurements were analyzed by the laboratory in Graz, Austria. The data was then statistically analyzed by using the Pearson correlation coefficient. (Abstract truncated at 2000 characters) | |
| Deskriptorji | HEART TRANSPLANTATION POSTOPERATIVE CARE ELECTROCARDIOGRAPHY EVOKED POTENTIALS HEART VENTRICLE HEART RATE CARDIAC PACING, ARTIFICIAL |