Avtor/Urednik		Ivanecz, Arpad; Potrč, Stojan; Horvat, Matjaž; Gadžijev, Eldar
Naslov		Kakšne so možnosti ozdravitve bolnika z jetrnimi zasevki raka debelega črevesa in danke?
Prevedeni naslov		What are the possibilities of cure for patients with colorectal liver metastases?
Tip		članek
Vir		Med Mes
Vol. in št.		Letnik 3, št. 4-5
Leto izdaje		2007
Obseg		str. 132-40
Jezik		slo
Abstrakt		Background. Liver resection, in collaboration with new diagnostic tools and chemotherapeutic agents, is the only potentially curative therapy for colorectal liver metastases (CRLM). The aim of the study is to present therapeutic options and to demonstrate our results of surgical treatment for patients with CRLM. Methods. In the period from 1.1.1996 to 31.12.2004 84 patients with CRLM underwent 110 procedures in our department. Results. The overall 5-year survival of patients with RO resection was 42% with median survival of 32.3 months. At the end of the study, 22 patients had no evidence of disease, 20 patients were alive with disease and 42 patients died of disease. The postoperative complication rate was 23.8%, mortality was 2.3%. Conclusion. We can offer a cure to some patients with CRLM, but only on the condition of a multidisciplinary approach in specialized centers in collaboration with surgeons, oncologists and radiologists.
Izvleček		Izhodišče. Resekcija jeter se je ob novih možnostih natančne diagnostike in uporabe kemoterapije do sedaj izkazala za edino potencialno kurativno terapijo jetrnih zasevkov raka debelega črevesa in danke (RDČD). Namen članka je predstaviti terapevtske možnosti in prikazati lastne rezultate pri kirurški oskrbi bolnikov z jetrnimi zasevki RDČD. Metode. V obdobju od 1.1.1996 do 31.12.2004 smo pri 84 bolnikih z jetrnimi zasevki RDČD skupaj opravili 110 posegov. Rezultati. Skupno 5-letno preživetje bolnikov z RO resekcijo je bilo 42% z medianim preživetjem 32.3 mesece. Ob zaključku analize je bilo 22 bolnikov živih brez recidiva obolenja, 20 bolnikov je bilo živih z recidivom obolenja, 42 bolnikov pa je umrlo zaradi napredovanja bolezni. Zapleti po operaciji so se pojavili pri 23.8% bolnikih, po-operativna smrtnost je bila 2.3%. Zaključek. Nekaterim bolnikom z jetrnimi zasevki RDČD lahko nudimo ozdravitev, vendar samo pod pogojem, da se zdravljenje vrši v usposobljenih centrih, kjer se odločitve glede vrste zdravljenja sprejemajo multidisciplinarno, v sodelovanju med kirurgi, onkologi ter radiologi.
Deskriptorji		COLORECTAL NEOPLASMS NEOPLASM METASTASIS LIVER NEOPLASMS HEPATECTOMY SURVIVAL ANALYSIS