Avtor/Urednik     Avčin, Tadej; Toplak, Nataša
Naslov     Antiphospholipid antibodies in response to infection
Tip     članek
Vir     Curr Rheumatol Rep
Vol. in št.     Letnik 9, št. 3
Leto izdaje     2007
Obseg     str. 212-8
Jezik     eng
Abstrakt     An association between infections and antiphospholipid antibodies (aPL) has been reported in several epidemiologic and experimental studies. Infection-induced aPL have been traditionally regarded as transient and were generally not associated with clinical features of antiphospholipid syndrome. The distinction between autoimmune and postinfectious aPL on the basis of requirement of binding cofactor is not absolute, and in recent years, several reports demonstrated that some patients can produce pathogenic antibodies in response to infection. Infections most frequently associated with antiphospholipid syndrome include parvovirus B19, cytomegalovirus, varicella-zoster virus, HIV, streptococcal and staphylococcal infections, gram-negative bacteria, and Mycoplasma pneumoniae.
Deskriptorji     INFECTION
ANTIBODIES, ANTIPHOSPHOLIPID
VIRUS DISEASES
BACTERIAL INFECTIONS