Avtor/Urednik		Osrajnik, Ilonka; Varga, Tomaž
Naslov		Fiziologija in patofiziologija dihalnega popuščanja
Prevedeni naslov		Physiology and patophysiology of respiratory failure
Tip		članek
Vir		In: Hojs R, Krajnc I, Pahor A, et al, editors. Zbornik predavanj in praktikum 18. srečanje internistov in zdravnikov splošne medicine Iz prakse za prakso z mednarodno udeležbo; 2007 jun 1-2; Maribor. Maribor: Univerzitetni klinični center,
Leto izdaje		2007
Obseg		str. 121-31
Jezik		slo
Abstrakt		Respiratory failure is a condition in which the respiratory system fails in one or both of its gas exchange functions: oxygenation of and carbon dioxide elimination from venous blood. Respiratory failure is defined as a partial pressure of oxygen in arterial blood (PaO2) of less than 8 kPa (60 mm Hg) or a partial pressure of carbon dioxide of more than 6.6 kPa (50 mm Hg) while breathing air at sea level. Respiratory failure can arise from an abormality in any of the components of the respiratory system: the central or peripheral nervous system, the respiratory muscles or chest wall, the airways or alveoli. Respiratory failure may be classified as hypoxemic or hypercapnic and may be either acute or chronic. The most important mechanisms that lead to hypoxemia are a reduction in inspired oxygen concentration, alveolar hyperventilation, alveolar vetilation and pulmonary perfusion mismatch, and abnormal diffusion of gases.