Avtor/Urednik | Požlep, B; Meleh, M; Kobal, B; Verdenik, I; Osredkar, J; Kralj, LZ; Meden-Vrtovec, H | |
Naslov | Use of lysophosphatidic acid un the management of benign and malignant ovarian tumors | |
Tip | članek | |
Vir | Eur J Gynaecol Oncol | |
Vol. in št. | Letnik 28, št. 5 | |
Leto izdaje | 2007 | |
Obseg | str. 394-9 | |
Jezik | eng | |
Abstrakt | Objective: To establish whether LPA determination improves the differentiation of benign from malignant ovarian tumors. - Methods: Total LPA-and LPA species in the serum were determined-using a novel method-in -142 patients with ultrasound (US) _ suspecious ovarian tumors and in 78 healthy women. All women underwent determination of CA125 in the serum, a vaginal US examination and morphology scoring of the tumor. Results: The levels of total LPA and its species in women with ovarian tumors were significantly higher from those in healthy women (p < 0.001). No significant difference was found in the levels of total LPA or any of its species between the women with benign and those with malignant ovarian tumors. Conclusions: Determination of serum LPA would be an appropriate test for ovarian tumor presence, especially in women of rcproductive age. The method however does not differentiate benign from malignant ovarian tumors. | |
Deskriptorji | OVARIAN NEOPLASMS LYSOPHOSPHOLIPIDS CA-125 ANTIGEN |