Avtor/Urednik		Grčevska, L; Polenakovič, M; Ferluga, D; Vizjak, A; Stavrič, G
Naslov		Membranous nephropathy with severe tubulointerstitial and vascular changes in a patient with psoriatic arthritis treated with non-steroidal anti-inflammatory drugs
Tip		članek
Vir		Clin Nephrol
Vol. in št.		Letnik 39, št. 5
Leto izdaje		1993
Obseg		str. 250-3
Jezik		eng
Abstrakt		We report on a patient who suffered from psoriasis vulgaris and psoriatic arthritis and developed nephrotic syndrome after long-term therapy with non-steroidal anti-inflammatory drugs. Membranous nephropathy with tubulointerstitial and vascular (intimal hyperplasia) changes were found on renal biopsy using optical, immunofluorescent and electron microscopy. Treatment with methylprednisolone "pulse" therapy (1 g/24 h during 3 days) and continuing with prednisone 0.5 mg/kg/24 h was ineffective and end-stage renal failure developed 6 months after the diagnosis had been established.
Deskriptorji		ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL ARTHRITIS, PSORIATIC GLOMERULONEPHRITIS, MEMBRANOUS KIDNEY ADULT ARTHRITIS, PSORIATIC BIOPSY GLOMERULONEPHRITIS, MEMBRANOUS KIDNEY FAILURE, CHRONIC METHYLPREDNISOLONE MICROSCOPY, ELECTRON FLUORESCENT ANTIBODY TECHNIQUE PREDNISONE TIME FACTORS