Avtor/Urednik | Meško-Brguljan, Pika; Cimerman, Nina | |
Naslov | Human cystain C | |
Tip | članek | |
Vir | Turk J Biochem | |
Vol. in št. | Letnik 32, št. 3 | |
Leto izdaje | 2007 | |
Obseg | str. 95-103 | |
Jezik | eng | |
Abstrakt | Cystatin C, a low molecular weight inhibitor of cysteine proteascs, is involved in various biological and pathological processes. Recently, scrum cystatin C has been proposed to be a valuable alternative marker of glomerular filtration rate, particularly in situations in which creatinine fails to provide an accurate estimate of renal impairment. However, the use of cystatin C is interfered by nonrenal factors such as glucocorticoid therapy, malignancy or thyroid disorders, which influence scrum cystatin C concentrations. The clinical utility of cystatin C as a renal marker is under evaluation. The standardisation of methods for cystatin C is necessary. | |
Deskriptorji | CYSTATINS GLOMERULAR FILTRATION RATE |