Avtor/Urednik     Berce, Ingrid; Mozetič-Wedom, Breda; Keše, Darja; Grmek-Košnik, Irena
Naslov     Ali obstaja povezava med kolitisom dojenčkov zdravljenih z antibiotiki in bakterijo Klebsiella species?
Prevedeni naslov     Is there any correlation between infantile colitis after antibiotic therapy and bacteria Klebsiella species?
Tip     članek
Vir     Med Razgl
Vol. in št.     Letnik 46, št. Suppl 2
Leto izdaje     2007
Obseg     str. 35-41
Jezik     slo
Abstrakt     Objective: To find out if Klebsiella spp. is responsible for mild colitis with colic in breastfed children aged < 1 year. Colics are a common problem in infants during the first 3 months of fife. A child with a colic episode can cry inconsolably. In most cases there is no good explanation or treatment for colic. When a colic is associated with the presence of blood and mucus in feces, parents usually visit the pediatrician. Methods: We have studied 24, aged < 1 year who were hospitalized at the pediatric ward of a regional hospital between 2002 and 2007 with the clinical diagnosis of mild haemorrhagic diarrhea with colic and in whom Klebsiella oxytoca or K. pneumoniae were isolated as the sole pathogen. Four strains of K. oxytoca and two strains of K. pneumoniae were tested for cytotoxul production using a tissue-culture assay. In addition, we have also studied infants of the same age with haemorragic diarrhea caused by detected pathogen. Results: Of a total of 24 newborns with cultures positive of Klebsiella oxytoca or K. pneumoniae 22 (91,6%) were breastfed and 15 (62,5%) were treated with antibiotic before the onset of intestinal disorders, mostly with a betalactam antibiotic (13/15). The mean age of the infants was 3 months (from 21 days to 11 months). The common clinical signs were: diarrhea in 79'%, abdominal colic in 45°/>, meteorism in 41%, blood and mucus in fecal specimens in 33% and vomiting in 33'%. No other common enteric pathogens were found in the 22/24 Klebsiella spp. positive patients. All 6 infants whose isolates were tested for cytotoxin received a betalactam antibiotic. All 6 tested Klehsiella spp. strains produced cytotoxin. In the control group of infants with haemorragic diarrhea in whom a known common pathogen was found, Klebsiella spp. was isolated twice (4,1%). (Abstract truncated at 2000 characters)
Deskriptorji     ANTIBIOTICS
COLITIS
KLEBSIELLA INFECTIONS
FECES
INFANT