| Avtor/Urednik | Ferk, Polonca; Leskošek, Branimir | |
| Naslov | Farmakogenomika in informacijski izzivi | |
| Prevedeni naslov | Pharmacogenomics and informatical challenges | |
| Tip | članek | |
| Vir | Inform Med Slov | |
| Vol. in št. | Letnik 13, št. 1 | |
| Leto izdaje | 2008 | |
| Obseg | str. 33-40 | |
| Jezik | slo | |
| Abstrakt | Pharmacogenomics is an interdisciplinary field which merges knowledge from pharmacology and genomics. Its basic aim is to find out how the unique genotype of an individual determines specific pharmacological responses. To be able to discover clinically relevant associations between the specific genotype and pharmacological response, huge amounts of data should be collected from different sources and further analyzed which is possible only by using suitable and effective informatics tools. In the paper a clinically relevant pharmacogenomic example is first presented and then contemporary informatics challenges are described. | |
| Deskriptorji | PHARMACOGENETICS POLYMORPHISM (GENETICS) GENOTYPE INFORMATION SYSTEMS CYTOCHROME P-450 CYP2D6 ALLELES BREAST NEOPLASMS TAMOXIFEN SURVIVAL ANALYSIS |