Avtor/Urednik		Kališnik, Jurij M; Avbelj, Viktor; Trobec, Roman; Vidmar, Gaj; Troise, Giovanni; Geršak, Borut
Naslov		Ventricular repolarization dynamicity and arrhythmic disturbances after beating-heart and arrested-heart revascularization
Tip		članek
Vir		Heart Surg Forum
Vol. in št.		Letnik 11, št. 4
Leto izdaje		2008
Obseg		str. E194-201
Jezik		eng
Abstrakt		Background: Arrhythmias attributable to altered autonomic modulation of the heart, with elevated sympathetic and depressed vagal modulation, occur to a similar extent after surgery performed on beating or arrested hearts. Coronary artery bypass grafting (CABG) with cardiopulmonary bypass has been associated with more frequent occurrence of arrhythmic events than surgery performed without CABG, even with comparable levels of postoperative cardiac autonomic (dis) regulation after arrested- and beating-heart revascularization. We explored the effects of arrested- and beating-heart revascularization procedures on the dynamics of ventricular repolarization and on increased postoperative arrhythmic events.Methods: Study participants included 57 CABG patients; 28 underwent on-pump and 29 underwent off-pump procedures. The 2 groups were comparable regarding clinical and postoperative characteristics. With high-quality 15-minute digital electrocardiograms, we assessed ventricular repolarization dynamics using RR and QT intervals and analyzed QT variability (QTV) and QT-RR interdependence. RR and QT intervals were determined from stationary 5-minute segments. QT-interval variability was determined by a T-wave template-matching algorithm. We used linear regression to compute the slope/correlation of the QT/RR interval. The Fisher exact test, nonpaired t-test, and ANOVA were applied to test the results; P <.05 was considered significant.Results: Postoperative arrhythmic events were significantly more frequent in both groups. One week postoperatively these events were significantly more frequent in the on-pump group. In both groups, the RR interval was shorter after CABG (P <.001). The QT variability index increased from -1.2 +/- 0.6 to -0.8 +/- 0.4 after off-pump CABG and from -1.3 +/- 0.5 to -0.5 +/- 0.6 on day 4 after surgery (P <.05), further deteriorating to -0.2 +/- 0.6 one week after CABG in the on-pump group only (P <.05). (Abstract truncated at 2000 characters)
Deskriptorji		CORONARY ARTERY BYPASS CARDIOPULMONARY BYPASS POSTOPERATIVE COMPLICATIONS ARRHYTHMIA ELECTROCARDIOGRAPHY MYOCARDIAL REVASCULARIZATION HEART RATE