Avtor/Urednik		Pajek, Jernej; Guček, Andrej; Kveder, Radoslav; Bučar-Pajek, Maja; Kaplan-Pavlovčič, Staša; Bren, Andrej F
Naslov		Impact of dialysis duration and glucose absorption on nutritional indices in stable continuous ambulatory peritoneal dialysis patients
Tip		članek
Vir		J Ren Nutr
Vol. in št.		Letnik 18, št. 6
Leto izdaje		2008
Obseg		str. 503-8
Jezik		eng
Abstrakt		Objective: The presence of comorbidity is a risk factor for both poor nutrition and poor outcome in continuous ambulatory peritoneal dialysis (CAPD) patients. In CAPD specifically, peritoneal glucose load is associated with a possible suppression of appetite, contributing to protein malnutrition. This study sought to explore the factors associated with malnutrition indices in stable peritoneal dialysis patients without significant comorbidity, and to assess the impact of peritoneal glucose absorption on nutrition parameters. Design: This was a cross-sectional observational study. Setting: This study took place in the peritoneal dialysis department of a university hospital, and involved outpatients. Patients: There were 23 stable, comorbidity-free CAPD patients (9 women), aged 54 +/- 12 years, with a CAPD duration of 28 +/- 25 months (values are mean +/- SD unless otherwise noted). Method: Nutritional status was evaluated by means of anthropometric and serum measurements. A peritoneal equilibration test was performed, and daily glucose absorption was measured. Lean body mass (LBM) was assessed through creatinine kinetics. Results: A significant impact of CAPD duration was found. Patients in the upper quartile of CAPD duration had worse nutritional parameters compared with the rest of the group: their mid-upper-arm surface area and fat surface area were lower (65 +/- 9 cm(2) vs. 78 +/- 6.2 cm(2) and 16 +/- 5.3 cm(2) vs. 26 +/- 9.5 cm(2), respectively, P < .05), their albumin concentration was lower (36 +/- 0.5 g/L vs. 42 +/- 4 g/L, P < .05), and their cholesterol and triglycerides were lower (3.5 +/- 0.5 vs. 5.2 +/- 1 mmol/L and 1.3 +/- 0.6 vs. 2.3 +/- 1.1 mmol/L, respectively, P < .05). No significant correlations between peritoneal glucose absorption and these indices were found. (Abstract truncated at 2000 characters)
Deskriptorji		PERITONEAL DIALYSIS, CONTINUOUS AMBULATORY NUTRITIONAL STATUS PROTEIN-ENERGY MALNUTRITION GLUCOSE CREATINE MIDDLE AGE CHOLESTEROL ALBUMINS TRIGLYCERIDES CROSS-SECTIONAL STUDIES