Avtor/Urednik		Ratkajec, Tihomir; Bilban, Marjan; Starc, Radovan
Naslov		Influence of psychosocial work-related factors on conventional risk factors of ischemic heart disease and homocysteine in Slovenian male workers
Tip		članek
Vir		Coll Antropol
Vol. in št.		Letnik 32, št. 2
Leto izdaje		2008
Obseg		str. 391-6
Jezik		eng
Abstrakt		The irnluence of psychosocial work-related factors on the conventional risk factors of ischemac heart dasease (IHD), particularly on the lipid changes and their effect on homocysteine is studied in this paper. Employed males aged 35 to 55 with angina pectoris or a myocardial infarction (IHD group) were compared to a group of individuals without ischemic heart disease (Control Group). Psychosocial factors were assessed using a Swedish Theorell questionnaire. The IHD Group was found to be at a higher rusk of IHD due to higher work demands (OR = 1.25), worse job control (OR = 1.23), frequent smoking (OR = 22), leadership positions (OR = 3.97), higher BMI (p = 0.059) and higher leaels of traglycerides (p = 0.005) arcd LDL-cholesterol (OR = 1.65). The level of HDL-cholesterol was sagnificantly lower (1.0 vs. 1.4 mmol/L, p < 0.001, OR =1,64), while the level of C-reactive protein (9.1 vs. 1.8 mg/L) and Interleukin-6 (6.5 vs. 1.6 rcglL) was higher. Homocysteine levels showed borderline significance (p = 0.056). Our study suggests a possible influence of psychosocial work-related factors on IHD risk factors, most of all on low HDL-cholesterol. No connection was found between psychosocial factors and the homocysteane level, shown to be an IHD risk factor at lower levels of approximately 10 micromol/L.
Deskriptorji		CORONARY DISEASE RISK FACTORS SMOKING ALCOHOL DRINKING CHOLESTEROL ADULT MIDDLE AGE HOMOCYSTEINE OCCUPATIONAL EXPOSURE SOCIOECONOMIC FACTORS QUESTIONNAIRES CASE-CONTROL STUDIES