Avtor/Urednik		Moller, Kasper; Olsson, Lisbeth; Piškur, Jure
Naslov		Ability for anaerobic growth is not sufficient for development of the petite phenotype in Saccharomyces kluyveri
Tip		članek
Vir		J Bacteriol
Vol. in št.		Letnik 183, št. 8
Leto izdaje		2001
Obseg		str. 2485-9
Jezik		eng
Abstrakt		Saccharomyces cerevisiae is a petite-phenotype-positive ("petite-positive") yeast, which can successfully grow in the absence of oxygen. On the other hand, Kluyveromyces lactis as well as many other yeasts are petite negative and cannot grow anaerobically. In this paper, we show that Saccharomyces kluyveri can grow under anaerobic conditions, but while it can generate respiration-deficient mutants, it cannot generate true petite mutants. From a phylogenetic point of view, S. kluyveri is apparently more closely related to S. cerevisiae than to K. lactis. These observations suggest that the progenitor of the modern Saccharomyces and Kluyveromyces yeasts, as well as other related genera, was a petite-negative and aerobic yeast. Upon separation of the K. lactis and S. kluyveri-S. cerevisiae lineages, the latter developed the ability to grow anaerobically. However, while the S. kluyveri lineage has remained petite negative, the lineage leading to the modern Saccharomyces sensu stricto and sensu lato yeasts has developed the petite-positive characteristic.
Deskriptorji		ANAEROBIOSIS CULTURE MEDIA MUTATION OXYGEN CONSUMPTION PHENOTYPE PHYLOGENY SACCHAROMYCES