Avtor/Urednik | Sawant, Prabha; Upadhyay, Amal P; Levičnik-Stezinar, Snežna; Zali, Mohammad R; Okamoto, Hiroaki | |
Naslov | Genotypes of GB virus C and hepatitis C virus in hepatitis patients in India, Iran and Slovenia | |
Tip | članek | |
Vir | Hepatology Research | |
Vol. in št. | Letnik 10 | |
Leto izdaje | 1998 | |
Obseg | str. 175-83 | |
Jezik | eng | |
Abstrakt | RNA of GB virus C (GBV-C) was detected in 12 of the 99 (12%) patients with chronic liver disease in India, including two of Il (18%) with antibody to hepatitis C virus (HCV), as well as in six of the 21 (29%) patients with anti-HCV in Iran and 16 of the 54 (30%) patients with anti-HCV in Slovenia. Of the 99 patients in India, 47 we re without serological markers of hepatitis B or C virus infection and four (9%) of them were positive for GBV-C RNA. Genotypes of GBV-C in the 34 samples from the three countries were invariably G2 that is prevalent in Europe and the United States. In contrast, the distribution of HCV genotypes we re much different among them with 2c, 4d and 5a detected locally, in addition to I/la, II/Ib and V/3a. These results indicate frequent GBV-C infection with genetic divergence much less than that of HCV in patients with chronic liver disease in India, Iran and Slovenia. | |
Deskriptorji | HEPATITIS C-LIKE VIRUSES HEPATITIS AGENTS, GB GENOTYPE HEPATITIS B SURFACE ANTIGENS HEPATITIS C ANTIGENS POLYMERASE CHAIN REACTION HEPATITIS, CHRONIC ACTIVE PHYLOGENY INDIA IRAN SLOVENIA |