Avtor/Urednik		Trnačević, S; Halilbašić, A; Ferluga, D; Plavljanić, Ð; Vizjak, A; Duraković, H; Habul, V; Mesić, E; Imamović, G; Hranisavljević, J; Pašić, M; Paunović, G
Naslov		Renal function, protein excretion and pathology of Balkan endemic nephropathy. 1. Renal function
Tip		članek
Vir		Kidney Int Suppl
Vol. in št.		Letnik 40, št. Suppl 34
Leto izdaje		1991
Obseg		str. S/49-S/51
Jezik		eng
Abstrakt		Renal function studies were performed on 59 patients who had the clinical criteria for Balkan endemic nephropathy (BEN). They were divided into three groups according to DTPA clearance (DTPA). Group 1. 11 individuals, had a mean age of 11.6 years and DTPA greather th. 100 ml/min. Group 2, 20 persons, had a mean age of 19 years and DTPA of 60 to 100 ml/min. Group 3 was made up of 28 people with a DTPA less th. 60 ml/min and an average age of 50.4 years. No distinguishing specific or characteristic symptoms of BEN were found in any of the three groups. Anemia was not found to be an early indicator when compared to other forms of progressive renal disease. Proteinuria was minimal and intermittent in all three groups. Maximum concentrating ability was significantly reduced only in the third group. These features do not allow the clinical differentiation of BEN from other chronic progress tubulointerstitial nephropathies. The geographic isolation and familial nature of the disease, associated with minimal proteinuria make BEN a unique entity. Kidney size by ultrasound was decreased in all three groups, suggesting that this may be another early and characteristic feature to BEN.
Deskriptorji		BALKAN NEPHROPATHY KIDNEY FAILURE SEVERITY OF ILLNESS INDEX KIDNEY CONCENTRATING ABILITY ANEMIA