Avtor/Urednik		Gunde-Cimerman, N; Plemenitaš, A; Cimerman, A
Naslov		Pleurotus fungi produce mevinolin, an inhibitor of HMG CoA reductase
Tip		članek
Vir		FEMS MICROBIOL LETT
Vol. in št.		Letnik 113, št. 3
Leto izdaje		1993
Obseg		str. 333-7
Jezik		eng
Abstrakt		Fungi of the genus Pleurotus were shown to produce the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor mevinolin. Crude methanol extracts and the purified inhibitor from three different species, P. sapidus, P. saca and P. ostreatus, were tested using the solubilized microsomal HMGCoA reductase from Chinese hamster ovary cells. The identity of the inhibitor was also confirmed by thin layer chromatography, high pressure liquid chromatography and mass spectroscopy.
Deskriptorji		HYDROXYMETHYLGLUTARYL COA REDUCTASES LOVASTATIN POLYPORACEAE CRICETULUS CHO CELLS HAMSTERS LOVASTATIN