Avtor/Urednik		Skok, Pavel; Ocepek, Andreja; Genslitskaya, Ekaterina; Kavalar, Rajko
Naslov		Peutz-Jegherjev sindrom: predstavitev bolnika in pregled literature
Prevedeni naslov		Peutz-Jeghers syndrome: presentation of a patient and literature review
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 78, št. 10
Leto izdaje		2009
Obseg		str. 570-5
Jezik		slo
Abstrakt		Introduction: Colorectal cancer carcinogenesis is a complex, long-lasting multistep process. Patients with dif erent polyposis syndromes, including Peutz-Jeghers, have signii cantly increased risk for dif erent types of cancer. Patients and methods: In this paper the authors are presenting a patient with Peutz-Jeghers syndrome, the clinical characteristics of this disease, molecular and genetic features, associations with carcinogenesis and screening possibilities. h is syndrome, characterized by the development of hamartomatous polyps in the gastrointestinal tract and mucocutaneus hiperpigmentations, was first described in a Dutch family in 1921 and is associated with increased risk of malignancy for the patient and his relatives.Conclusions: Early diagnosis of Peutz-Jeghers syndrome is important for the prevention and/or early detection of cancer.
Deskriptorji		PEUTZ-JEGHERS SYNDROME COLONOSCOPY AGED