Avtor/Urednik		Logonder-Mlinšek, M; Pajer, Z
Naslov		The long-term effect of a calcium diet on the bone tissue, C-cells and parathyroid glands of the rat
Tip		članek
Vir		J Endocrinol Invest
Vol. in št.		Letnik 16
Leto izdaje		1993
Obseg		str. 687-90
Jezik		eng
Abstrakt		In this experiment of 11 month-duration, 18 female Wistar rats received controlled amounts of calcium with food and water, to produce a state of either hypocalcemia or hypercalcemia. After a long-term low calcium diet hypocalcemia disappeared. This group of animals showed insignificant increases in the nuclear-cytoplasmic ratio of the parathyroid cells as well as in the total volume of the parathyroid glands, and a significant increase in the volume density of the osteoid. In the group receiving a high calcium diet, hypercalcemia was still present after 11 month. The insignificantly smaller and more numerous C-cells produced more calcitonin than normally. The parathyroid cells were significantly smaller and the numerical areal density of the osteoclasts was significantly lower than in the control group. It can be concluded that the parathyroid glands and C-cells are involved in the maintenance of blood calcium homeostasis during a long-term experiment on rats receiving low or high calcium diet.
Deskriptorji		CALCIUM CALCIUM, DIETARY PARATHYROID GLANDS CALCITONIN BONE DENSITY RATS, WISTAR HOMEOSTASIS HYPERCALCEMIA HYPOCALCEMIA TIME FACTORS PARATHYROID HORMONES RATS