Avtor/Urednik		Tepeš, Bojan; Ojsteršek, Zvezdana
Naslov		Uspešnost zdravljenja okužbe z bakterijo Helicobacter pylori v Sloveniji v letu 2008
Prevedeni naslov		Cumulative Helicobacter pylori eradication rates in Slovenia in the year 2008
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 79, št. 1
Leto izdaje		2010
Obseg		str. 19-24
Jezik		slo
Abstrakt		Background: The aim of the study was to examine cumulative Helicobacter pylori eradication rates in Slovenia in the year 2008 that can be achieved in clinical practice by clasic first and second regimens suggested by Maastricht recommendations and third line empirical regimens. Methods: We performed cross sectional study that included 500 consecutive patients, who underwent urea breath test aft er Helicobacter pylori eradication regimens in AM DC Rogaška in the period from January to September 2008.We analysed eradication rates after OMC regimen, 7 days (omeprazole, metronidazole, clarithromycin), OAC regimen, 7 days (omeprazole, amoxicillin, clarithromycin), BMTO regimen, 14 days (colloid bismuth subcitrate, metronidazole, oxytetracycline, omeprazole) and OA regimen, 14 days (omeprazole, amoxicillin). Results: Total 308 patients received OMC regimen with eradication rate 78.6 % (95 % CI 76.3%-80.9%). Total 80 patients received OAC regimen with eradication rate 80 % (95 % CI 75.6 - 84.4 %). After failure of the first regimen, they received the opposite first-line regimen. In the case of eradication failure, 23 patients received BMTO regimen as a third-line therapy with eradication rate 82.6 % and 14 patients received OA regimen with eradication rate 64.3 %. Nine of 388 patients who started Helicobacter pylori eradication treatment in our study remained positive aft er they received all the available therapeutical regimens (2,3 %). Conclusions. Cumulative Helicobacter pylori eradication rate in Slovenia in the year 2008 is still very high-97.7 %. These results are comparable with the results in other European countries.
Deskriptorji		HELICOBACTER INFECTIONS HELICOBACTER PYLORI UREA OMEPRAZOLE METRONIDAZOLE CLARITHROMYCIN STOMACH ULCER DUODENAL ULCER GASTRITIS TREATMENT OUTCOME CROSS-SECTIONAL STUDIES