Avtor/Urednik     Verhoef, L; Poljšak-Prijatelj, M; Barlič-Maganja, D; Hočevar-Grom, A
Naslov     Use of norovirus genotype profiles to differentiate origins of foodborne outbreaks
Tip     članek
Vir     Emerg Infect Dis
Vol. in št.     Letnik 16, št. 4
Leto izdaje     2010
Obseg     str. 617-24
Jezik     eng
Abstrakt     Because secondary transmission masks the connection between sources and outbreaks, estimating the proportion of foodborne norovirus infections is difficult. We studied whether norovirus genotype frequency distributions (genotype profiles) can enhance detection of the sources of foodborne outbreaks. Control measures differ substantially; therefore, differentiating this transmission mode from person-borne or food handler-borne outbreaks is of public health interest. Comparison of bivalve mollusks collected during monitoring (n = 295) and outbreak surveillance strains (n = 2,858) showed 2 distinguishable genotype profiles in 1) human feces and 2) source-contaminated food and bivalve mollusks; genotypes I.2 and I.4 were more frequently detected in foodborne outbreaks. Overall, approximately 21% of all outbreaks were foodborne; further analysis showed that 25% of the outbreaks reported as food handler-associated were probably caused by source contamination of the food.
Deskriptorji     DISEASE OUTBREAKS
CALICIVIRIDAE INFECTIONS
FOOD CONTAMINATION
SHELLFISH
CALICIVIRIDAE
FECES
GENOTYPE
BASE SEQUENCE