Avtor/Urednik		Takač, I; Vlaisavljević, V
Naslov		Preprečevanje pooperativnih zarastlin po mikrokirurški operaciji
Prevedeni naslov		Prevention of postoperative adhesion formation after microsurgical operation
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 63, št. 6-7
Leto izdaje		1994
Obseg		str. 365-7
Jezik		slo
Abstrakt		Background. The efficacy of normal saline and hydrocortisone in the prevention of postoperative adhesions was examined. Methods. The uterine horns of 30 rats were subjected to both division and microsurgical anastomosis of proximal segment and bipolar electrocoagulation of the distal segment. They were randomly divided into three equal groups: first group received normal saline perioperatively, second group received hydrocortisone in normal saline perioperatively and hydrocortisone postoperatively and third group was a control without medication. At repeat laparotomy 2 weeks later the intraperitoneal adhesions were graded from 0 to 3 according to their severity. Separate adhesions scores were assigned to the areas of anastomosis and electrocoagulation. Results. Total adhesion scores were 71 for control group. 64 for normal saline group and 52 for hydrocortisone group. The hydrocortisone group formed significantly fewer adhesions than control group (p less th. 0.05). Althrough the normal saline treated rats had less adhesions than the controls, the difference was not significant. Conclusions. These results suggest that in this species the hydrocortisone given in normal saline perioperatively and as a single agent postoperatively is effective in preventing postoperative adhesions formation after microsurgical operation.
Deskriptorji		POSTOPERATIVE COMPLICATIONS ADHESIONS HYDROCORTISONE MICROSURGERY ANIMALS, LABORATORY RATS UTERUS