Avtor/Urednik		Cinco, M
Naslov		Isolation and antigenic variability of Borrelia burgdorferi
Tip		članek
Vir		Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.		Letnik 3, št. 1-2
Leto izdaje		1994
Obseg		str. 33-6
Jezik		eng
Abstrakt		Organisms of the species B. burgdorferi sensu lato are isolated from ticks, mainly of the genus Ixodes, and hosts- birds and mammals- by different sampling and using BSK medium. Isolation for diagnostic purposes, is the best demonstration of the etiology of the infection, but it is not always successful due to the paucity of spirochetes in the body. Strains of Borrelia burgdorferi undergo antigenic variations, which affect Osp main proteins and also LOS. Some of these antigenic changes studied in the so-called "escape mutants" on a molecular point of view showed to be due to intraplasmid recombinations, at the Osp gene sequences. These mutations can play an important role during the Borrelia infection "in vivo".
Deskriptorji		BORRELIA BURGDORFERI ANTIGENIC VARIATION LYME DISEASE