Avtor/Urednik		Bogataj, M; Mrhar, A; Korošec, L
Naslov		In vitro evaluation of bioadhesive properties of hydroxypropylcellulose and carboxymethylcellulose films and microspheres
Tip		članek
Vir		In: Crommelin D, Couvreur P, Duchene D, editors. In vitro and ex vivo test systems to rationalize drug design and delivery. Europen symposium; 1993 13-14 Dec; Paris. Paris: International pharmaceutical federation,
Vol. in št.		, št. 2
Leto izdaje		1994
Obseg		str. 228-31
Jezik		eng
Abstrakt		The method for measuring bioadhesive force was applied to evaluate bioadhesive properties of hydroxypropylcellulose and sodium carboxymethylcellulose films and microspheres. The guinea pig small intestine was used as mucosal tissue. The quantities of water needed for complete hidration of polymers and microspheres were also determined. Correlation with bioadhesion force for different samples of microspheres was performed, too. In addition the influence of different quantities of water used for hidration of polymers and microspheres on the bioadhesive strength was studied.
Deskriptorji		INTESTINAL MUCOSA ADHESIVENESS CELLULOSE MICROSPHERES PIPEMIDIC ACID STEARATES WATER