Avtor/Urednik		Šarc, Irena
Naslov		Obravnava, srčnožilne bolezni in prognoza bolnikov hospitaliziranih zaradi kronične obstruktivne pljučne bolezni
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje		2010
Obseg		str. 69
Jezik		slo
Abstrakt		Background: Chronic obstructive pulmonary disease is characterized by progressive airway obstruction, which is the cause of high morbidity and mortality. Pharmacological treatment primarity offers symptom relief with improved quality of life. Guideline implementation was found less than optimal in previous studies. Cardiovascular diseases are the most important comorbidity in patients with COPD with important prognostic imapact. Aims: Our aim was to establish presciption patterns of COPD medication and implementation of guidelines. We also aimed to determine prevalence, therapy and prognostic implications of concommitant cardiovascular disease. Subjects and methods: We retrospectively reviewed ll discharges in University Clinic Golnik from February 2002 to June 2007 for presence of primary diagnosis of COPD as coded accoring to ICD 10. Diagnosis was ascertained by review of medical records, we excluded all without diagnostic criteria for COPD diagnosis. Vital status was obtained from Central Population Registry, the database was censored on November 1st, 2008. Results: Final sample consisted of 1185 patients with average age of 71.8 years, 72% men, 64% GOLD III/IV. Most frequent comorbiditx were cardiovascular disease (62% - 40% arterial hypertension, 30% heart failure, 20% atrial fibrilation). 62% of patients were discharged with three or more drugs; 3% had no regular drugs. In 15% of patients ICSs were overprescribed and 4% of patient in GOLD I(I-IV had no regular bronchodilator treatment. Prescription rates of LABAs, tiotropium and ICS increased over the disease continuum (p>0.0001). Beta blockers were underprescribed in patients with heart failure and ischemic heart disease (6% and 16%). Abstract truncated at 2000 characters.
Deskriptorji		LUNG DISEASES, OBSTRUCTIVE HOSPITALIZATION GLUCOCORTICOIDS CHOLINERGIC ANTAGONISTS ADRENERGIC BETA-AGONISTS PROGNOSIS SURVIVAL ANALYSIS COMORBIDITY HEART FAILURE, CONGESTIVE ATRIAL FIBRILLATION MYOCARDIAL ISCHEMIA HYPERTENSION DIABETES MELLITUS