Avtor/Urednik | Blazek, Dalibor; Peterlin, Matija B | |
Naslov | Tat-SIRT1 tango | |
Tip | članek | |
Vir | Mol Cell | |
Vol. in št. | Letnik 29, št. 5 | |
Leto izdaje | 2008 | |
Obseg | str. 539-40 | |
Jezik | eng | |
Abstrakt | In a recent issue of Cell Host & Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation. | |
Deskriptorji | ACQUIRED IMMUNODEFICIENCY SYNDROME ANIMALS HIV-1 MICE NF-KAPPA B T-LYMPHOCYTES TRANSCRIPTION, GENETIC |