Avtor/Urednik     Blazek, Dalibor; Peterlin, Matija B
Naslov     Tat-SIRT1 tango
Tip     članek
Vir     Mol Cell
Vol. in št.     Letnik 29, št. 5
Leto izdaje     2008
Obseg     str. 539-40
Jezik     eng
Abstrakt     In a recent issue of Cell Host & Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation.
Deskriptorji     ACQUIRED IMMUNODEFICIENCY SYNDROME
ANIMALS
HIV-1
MICE
NF-KAPPA B
T-LYMPHOCYTES
TRANSCRIPTION, GENETIC