Avtor/Urednik		Šuštar, Maja; Hawlina, Marko; Brecelj, Jelka
Naslov		Electroretinographic evaluation of the retinal S-cone system
Tip		članek
Vir		Doc Ophthalmol
Vol. in št.		Letnik 123, št. 3
Leto izdaje		2011
Obseg		str. 199-210
Jezik		eng
Abstrakt		The aim of this study was to differentiate S-cone responses from other retinal activities using various recording conditions and to optimize these recording conditions for clinical diagnostics. S-cone responses to blue stimuli (449 nm) were studied in 20 healthy subjects and four patients with enhanced S-cone syndrome. The time-integrated luminance of the stimulus varied from 0.008 to 1.0 cd s/m(2). Three isoluminant backgrounds were used (100 ph cd/m(2) = 40 sc cd/m(2)): amber (594 nm), green (513 nm), and red (635 nm). With low flash strengths (from 0.008 to 0.032 cd s/m(2)), the S-cone response appeared as a single positive peak, while with higher strengths (>/=0.064 cd s/m(2)), it appeared as a second peak that followed the L-cone and M-cone components. With a further increase in flash strength (>/=0.25 cd s/m(2)), the S-cone response interfered with the i-wave of the L-cone and M-cone systems. The wavelength and luminance of the background influenced the suppression of the rods, as well as the L-cone- and M-cone-system activities. The S-cone response was measurable in the presence of the amber and green backgrounds, but its amplitude was higher if a strong red background was used. Thus, the function of the retinal S-cone system can be measured if possible interference from other retinal sources can be minimized by the appropriate combination of stimulus and background parameters.
Deskriptorji		ELECTRORETINOGRAPHY CONES (RETINA) VISUAL ACUITY MUTATION RETINAL DISEASES LUMINESCENCE ADULT