Avtor/Urednik		Strojnik, Tadej; Flisar, Dušan; Drstvenšek, Igor
Naslov		Treatment of movement disorders using deep brain stimulation - illustrative case reports and technical notes
Prevedeni naslov		Stimulacija globokih možganskih jeder za zdravljenje motenj gibanja - prikaz primerov in tehničnih izboljšav
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 81, št. 5
Leto izdaje		2012
Obseg		str. 422-34
Jezik		eng
Abstrakt		Operative neuromodulation is the field of electrically or chemically altering the signal transmission in the nervous system by implanted devices in order to excite, inhibit or tune the activities of neurons or neural networks to produce therapeutic effects. Deep brain stimulation (DBS) is an important component of the therapy of movement disorders and has almost completely replaced high-frequency coagulation of brain tissue in stereotactic neurosurgery. This article presents the first DBS cases in Slovenia. In the article the technical features and adjustments of magnetic resonance (MR) imaging and development of a new microdrive, which was clinically successfully tested, are described and discussed.
Izvleček		Operacijska nevromodulacija je reverzibilna uporaba električne stimulacije ali dovajanje farmakoloških snovi v osrednji živčni sistem z vgradnjo naprave v bolnikov telo. Namen je spreminjati aktivnost živčnega sistema (ekscitacija, inhibicija ali prilagajanje nevronov ali nevronske mreže) za zdravljenje specifičnih stanj. Globoka možganska stimulacija (GMS) je pomembna metoda za zdravljenje gibalnih motenj in je skoraj popolnoma nadomestila visokofrekvenčno koagulacijo možganovine. V članku predstavljamo prve slovenske primere GMS. Predstavili smo tehnične posebnosti in prilagoditve pri uporabi magnetne resonance ter razvoj novega mikrovodila, ki smo ga uspešno klinično preizkusili.
Deskriptorji		MOVEMENT DISORDERS PARKINSON DISEASE STEREOTAXIC TECHNIQUES MAGNETIC RESONANCE IMAGING