Avtor/Urednik     Falnoga, I; Mrhar, A; Karba, R; Stegnar, P; Škreblin, M; Tušek-Žnidarič, M
Naslov     Mercury toxicokinetics in Wistar rats exposed to elemental mercury vapour: modeling and computer simulation
Tip     članek
Vir     Arch Toxicol
Vol. in št.     Letnik 68, št. 7
Leto izdaje     1994
Obseg     str. 406-15
Jezik     eng
Abstrakt     The kinetics of total mercury (Hg) absorption, distribution and elimination in Wistar rats exposed for long periods to elemental mercury vapour (Hg zero) in the Idrija mercury mine were studied. From the experimental data base a compartmental model was built as a framework for experimental data interpretation and prediction of organ mercury levels under different conditions. Using the model the exposures of rats under conditions comparable to those of professionally exposed workers (mercury miners, workers in the chloralkali industry) and individuals with amalgam fillings were simulated.
Deskriptorji     COMPUTER SIMULATION
MERCURY
MERCURY
MODELS, BIOLOGICAL
RATS
RATS, WISTAR
TISSUE DISTRIBUTION
VOLATILIZATION