Avtor/Urednik		Guček, A; Bren, AF; Lindič, J; Hergouth, V; Mlinšek, D
Naslov		Is monotherapy with cefazolin or ofloxacin an adequate treatment for peritonitis in CAPD patients?
Tip		članek
Vir		Adv Perit Dial
Vol. in št.		Letnik 10
Leto izdaje		1994
Obseg		str. 144-6
Jezik		eng
Abstrakt		This prospective randomized study is an evaluation of efficacy of cefazolin and ofloxacin in 23 end-stage renal disease (ESRD) patients treated with continuous ambulatory peritoneal dialysis (CAPD) who experienced 38 episodes of peritonitis (P). Cefazolin was administered intraperitoneally: 1000 mg as loading dose and 250 mg every exchange as maintenance dose for ten days. Ofloxacin was given orally: first 300 mg, followed by ten daily doses of 200 mg. Microbes most frequently isolated from peritoneal effluent were Staphylococci (coagulase-negative in 55.3 percent, aureus in 7.9 percent), Acinetobacter (in 5.3 percent), Klebsiella (in 5.5 percent), and Micrococcus (in 5.3 percent). Used as monotherapy, we found the efficacy of both cefazolin and ofloxacin inadequate for treatment of P in CAPD patients (cefazolin 65 percent, ofloxacin 67 percent) (NS).
Deskriptorji		CEFAZOLIN OFLOXACIN PERITONEAL DIALYSIS, CONTINUOUS AMBULATORY PERITONITIS ADULT AGED MIDDLE AGE PERITONITIS PROSPECTIVE STUDIES