Avtor/Urednik		Ekart, Robert; Kovačič Grobelšek, Vesna; Dai, Klara; Černelč, Peter; Hojs, Radovan
Naslov		Rare manifestation of the thrombotic microangiopathy in a patient with sarcoidosis, common variable immunodeficiency and large B-cell non-hodgkin lymphoma
Tip		članek
Vol. in št.		Letnik 48, št. 3
Leto izdaje		2013
Obseg		str. 345-347
ISSN		1473-0502 - Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Jezik		eng
Abstrakt		58-year old Caucasian woman was diagnosed with sarcoidosis. Low immunoglobulin levels were found and common variable immunodeficiency (CVID) was diagnosed 1year later. Laboratory tests and clinical course at this time revealed thrombotic microangiopathy (TMA). Therapeutic plasma exchange was started and her clinical status and laboratory parameters improved. According to CVID she received human immunoglobulin intravenously. Four months later we noticed swelling of the parotid glands and generalized lymphadenopathy. Histology of cervical lymph node confirmed large B-cell non-Hodgkin lymphoma (B-cell NHL). To the best of our knowledge, TMA complicating the course of sarcoidosis, CVID and B-cell NHL has never been reported.
Proste vsebinske oznake		mikroangiopatija, trombotična sarkoidoza ne-Hodgkinsov limfom B-celic imunska pomanjkljivost znaki in simptomi