Avtor/Urednik		Kotnik, V; Čižek-Sajko, M; Ihan, A; Simčič, S; Wraber, B; Štalc, A
Naslov		Natural and artificial immunomodulation
Prevedeni naslov		Naravna in umetna imunomodulacija
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 63, št. Suppl 2
Leto izdaje		1994
Obseg		str. II-49-II-5
Jezik		slo
Abstrakt		Background. Immunomodulation is an natural event. It is important in the development of the disease and healing. Understanding of these natural events leads to the production of natural and artificial substances useful for the therapy. Some of them carz increase, some decrease the selected immune defence activities. A lot more is known about immunosuppressants than about immunostimulators. In the presentation the authors discuss some natural and artificial immunomodulatory mechanisms to elucidate the complexity of these events, supporting their opinion with experimental data. First they discuss Il-2/soluble Il-2 receptor system, where attempt was made to present the regulatory role of soluble Il-2R molecule. Next the authors discuss the problem of target recognition by NK cells. The possible involvement of an IFN gamma-like molecule originating from the target cell is proposed to be of significance.
Deskriptorji		LYMPHOCYTE TRANSFORMATION INTERLEUKIN-2 RECEPTORS, INTERLEUKIN-2 KILLER CELLS, NATURAL ANTIBODIES, MONOCLONAL KILLER CELLS INTERFERONS