Avtor/Urednik		Hinni, Michael L.; Strojan, Primož
Naslov		Surgical margins in head and neck cancer
Tip		članek
Vol. in št.		Letnik 35, št. 9
Leto izdaje		2013
Obseg		str. 1362-1370
ISSN		1097-0347 - Head & neck
Jezik		eng
Abstrakt		Adequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relatingto the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as molecular margins and contact microscopic endoscopy, However, the limitations of these approaches need to be understood. The goal of this review was to evaluate these issues to define a more rational, standardiyed approach for achieving resection margin adequacy for patients with HNSCC undergoing curative resection.
Deskriptorji		Head and neck neoplasms Neoplasm invasiveness Intraoperative period Frosen sections Carcinoma, squamous cell Surgery Pathology
Proste vsebinske oznake		rak glave rak vratu onkologija