| Avtor/Urednik | Hojs-Fabjan, Tanja | |
| Naslov | Zdravljenje multiple skleroze z natalizumabom | |
| Prevedeni naslov | Use of natalizumab in the treatment of multiple sclerosis | |
| Tip | članek | |
| Vir | 260477184 | |
| Vol. in št. | Letnik 50, št. suppl. 6 | |
| Leto izdaje | 2011 | |
| Obseg | str. 19-25 | |
| Jezik | slv | |
| Abstrakt | Multipla skleroza je kronična avtoimuska vnetna demielinizacijska ter degenerativna bolezen osrednjega živčevja. Natalizumab je humanizirano monoklonsko protitelo, ki je učinkovito za zdravljenje recidivno remitentne multiple skleroze. V prispevku je prikazana učinkovitost ter varnost zdravljenja multiple skleroze z natalizumabom, pravilna izbira bolnikov in ukrepanje v primeru pojava neželenih učinkov ali v primeru progresivne multifokalne encefalopatije zaradi tega načina zdravljenja.Multiple sclerosis is a chronic autoimmune inflammatory and neurodegenerative disorder of the central nervous system. Natalizumab, a humanized monoclonal antibody, is highly effective in the treatment of relapsing multiple sclerosis. The article presents the effectivenes and safety data on the treatment of multiple sclerosis with natalizumab, appropriate patient selection and the management of adverse effects, along with cases of progressive multifocal leukoencephalopathy provoked by this type of treatment. | |
| Deskriptorji | Multiple Sclerosis Multipla skleroza Biological Agents Biološka zdravila Natalizumab Natalizumab Leukoencephalopathy, Progressive Multifocal Progresivna multifokalna encefalopatija Drug therapy Zdravljenje z zdravili |