Avtor/Urednik		Mlakar, Polona; Salobir, Barbara; Čobo, Nusret; Jug, Borut; Terčelj-Zorman, Marjeta; Šabovič, Mišo
Naslov		The effect of short-term cardiac rehabilitation after acute myocardial infarction on high-sensitivity c-reactive protein
Tip		članek
Vol. in št.		Letnik 12, št. 2
Leto izdaje		2014
Obseg		str. 149-155
ISSN		1540-4196 - Metabolic syndrome and related disorders
Jezik		eng
Abstrakt		Background: High-sensitivity C-reactive protein (hsCRP) is an important biomarker of risk for coronary heart disease morbidity and mortality. We investigated the influence of short-term cardiac rehabilitation (CR) after acute myocardial infarction (AMI) on values of hsCRP and classical risk factors, including metabolic syndrome. Methods: hsCRP and classical risk factors were measured before and after completed 2-week CR program in 30 men after AMI. The comparison group comprised 30 age-balanced healthy men, with no risk factors for coronary heart disease. Results: As expected, in comparison to healthy individuals, patients had higher values of hsCRP; furthermore, smokers had significantly higher hsCRP values than nonsmokers. Patients had more expressed markers of metabolic syndrome and due to pharmacological therapy lower blood pressure, total cholesterol and low-density lipoprotein cholesterol (LDL-C). After CR was completed, a significant drop in hsCRP (P=0.006) and improvement of metabolic syndrome parameters (lower body mass index, blood pressure, LDL-C, triglycerides) was observed in nonsmokers, whereas no such changes occurred in smokers. Conclusions: Our study revealed that hsCRP and metabolic syndrome parameters can be substantially reduced by a 2-week CR program; however, this effect is present only in nonsmokers. Thus, all patients entering the CR program after AMI should be advised to quit smoking before entering the program to achieve optimal benefits.
Proste vsebinske oznake		rehabilitation acute myocardial infarction