Avtor/Urednik		Goto, M; Yoshioka, T; Ravindranath, T; Battelino, T; Young, RI; Zeller, WP
Naslov		LPS injected into the pregnant rat late in gestation does not induce fetal endotoxemia
Tip		članek
Vir		Res Commun Mol Pathol Pharmacol
Vol. in št.		Letnik 85, št. 1
Leto izdaje		1994
Obseg		str. 109-12
Jezik		eng
Abstrakt		End toxin is abortifacient. Abortion may be due to maternal, fetal or combined endotoxemia. The present study was performed to evaluate if fetal rat endotoxemia was induced by maternal endotoxemia in late gestation. An intraperitoneal injection of smooth lipopolysaccharide (Escherichia coli LPA nad Shigella flexneri LPS) or rough LPS (Rc mutant Escherichia coli LPS) induced Limulus activity in maternal plasma, but not fetal plasma. These results suggest that fetal rat endotoxemia is not induced during maternal endotoxemia. Thus, the abortion may not be due to fetal endotoxemia.
Deskriptorji		ENDOTOXINS FETAL DISEASES LIPOPOLYSACCHARIDES PREGNANCY TOXEMIAS RATS ANIMALS, LABORATORY ESCHERICHIA COLI FETAL BLOOD GESTATIONAL AGE LIMULUS TEST SHIGELLA FLEXNERI