Avtor/Urednik		Brvar, Miran
Naslov		Klinično pomembne razlike, prepoznava in ukrepi pri predoziranju benzodiazepinov
Prevedeni naslov		Clinical features, diagnosis and treatment of benzodiapine overdose
Tip		članek
Vol. in št.		Letnik 65, št. 1
Leto izdaje		2014
Obseg		str. 18-23
ISSN		0014-8229 - Farmacevtski vestnik
Jezik		slv
Abstrakt		Benzodiazepines are the most common group of drugs used in deliberate self-poisoning in Slovenia. The most frequently benzodiazepine poisoning include alprazolam, diazepam, bromazepam, lorazepam and flurazepam. Patients with a mild benzodiazepine overdose display drowsiness, dysarthria and ataxia. In large doses, benzodiazepine can cause coma and respiratory depression, and death. Flumazenil, which is a competitive antagonist of GABA receptors, can help to confirm a suspected diagnosis of benzodiazepine overdose in unconsciousness poisoned patients. The management of acute benzodiazepine poisoning is mainly supportive. In addition, flumazenil and activated charcoal could be used.
Proste vsebinske oznake		benzodiazepini zastrupitve predoziranja benzodiazepine poisoning overdose