Avtor/Urednik		Rot, Uroš; Horvat-Ledinek, Alenka
Naslov		Interferons beta have vasoconstrictive and procoagulant effects: a woman who developed livedo reticularis and Raynaud phenomenon in association with interferon beta treatment for multiple sclerosis
Tip		članek
Vir		In: Proceedings of the 6th Dubrovnik International Conference on Multiple Sclerosis, Dubrovnik, Croatia, 10-12 May 2012 Assen : Elsevier
Leto izdaje		2013
Obseg		str. S79-S81
Jezik		eng
Abstrakt		A 31-year-old woman with MS developed livedo reticularis and secondary Raynaud phenomenon 2.5 years after introduction of interferon beta-1b. The symptoms disappeared after withdrawal of the drug. Livedo reticularis and Raynaud phenomenon as well as pulmonary arterial hypertension, venous sinus thrombosis, pulmonary embolism and renal thrombotic microangiopathy have all been described in association with interferon beta therapy. These complications strongly suggest that type I interferons have vasoconstrictive and procoagulant effects with potentially serious systemic complications.
Proste vsebinske oznake		multiple sclerosis Interferon beta Side effects Raynaud phenomenon Livedo reticularis