| Avtor/Urednik | Kikelj, Danijel | |
| Naslov | Sodobna sintezna zdravila za zdravljenje astme | |
| Prevedeni naslov | Modern synthetic drugs for treatment of asthma | |
| Tip | članek | |
| Vol. in št. | Letnik 64, št. 2 | |
| Leto izdaje | 2013 | |
| Obseg | str. 129-136 | |
| ISSN | 0014-8229 - Farmacevtski vestnik | |
| Jezik | slv | |
| Abstrakt | Astma je kronična bolezen dihalnih poti, za katero sta značilni brohokonstrikcija in vnetje. Delovanje učinkovin za obvladovanje in zdravljenje astme je usmerjeno prvenstveno proti obema patofiziološkima problemoma. V tem članku podajamo pregled sodobnih sinteznih učinkovin za zdravljenje astme, ki vključujejo bronhoselektivne adrenergične [beta]2 agoniste, antiholinergične učinkovine, glukokortikoide, inhibitorje biosinteze levkotrienov in antagoniste levkotrienskih receptorjev ter inhibitorje fosfodiesteraz.Asthma is a chronic airway disorder characterized by airflow obstruction and an underlying inflammation. Asthma symptoms are caused by bronchoconstriction and inflammation, and therapeutical approached are directed at both of these patophysiological problems. The paper brings an overview of modern synthetic drugs for treatment and management of asthma, including bronchoselective adrenergic [beta]2 agonists, anticholinegics, glucocorticoids, leukotriene biosynthesis inhibitors, leukotriene receptor antagonists and phosphodiesterase inhibitors. | |
| Proste vsebinske oznake | astma zdravila |