Avtor/Urednik		Pahor, Artur; Pahor, Dušica
Naslov		PRECLUDE Pericardial Membrane für die Behandlung von perforiertem Hornhautulkus bei Patienten mit systemischen autoimmunentzündlichen Erkrankungen
Tip		članek
Vol. in št.		Letnik 28, št. Hft. 4
Leto izdaje		2014
Obseg		str. 160-166
Jezik		ger
Abstrakt		Purpose To evaluate the use of PRECLUDE Pericardial Membrane composed of expanded polytetrafluoroethylene (e-PTFE, widely known as Gore-Tex) as an alternative surgical procedure for the management of perforated corneal ulcer closure in patients with systemic autoimmune inflammation. Methods Medical records of all patients who were admitted to our department and underwent surgical repair of perforated corneal ulcer with PRECLUDE pericardial membrane between December 2009 and December 2013 were retrospectively reviewed. In 3 patients with systemic autoimmune inflammation non-absorbable, microporous, watertight 0.1 mm thick e-PTFE membrane was used for corneal ulcer closure. Proper size of membrane was cut to overlap the defect adequately and to achieve a desired tissue attachment. Membrane was fixated with several nonabsorbable sutures. Results Corneal perforation was successfully covered with e-PTFE membrane. None of the patients had pain or discomfort. No signs of infections or inflammations were detected on follow-up examinations. Three months after surgical treatment the e-PTPE membrane was removed in patient with granulomatosis with polyangiitis and in patient with systemic vasculitis and eight months after surgery in patient with Sjögren syndrome. Underlying cornea was thin, firm, stable and completely vascularised. Conclusion PRECLUDE Pericardial Membrane was found to be a safe and effective as an alternative surgical procedure for perforating corneal ulcer closure in patients with systemic autoimmune inflammation. In these high risk patients for graft rejections this procedure could be the method of choice for eye preservation and for delayed corneal transplantation. Further studies are necessary to confirm our results.
Proste vsebinske oznake		avtoimuno vnetje, sistemsko roženica ulkus, perforacija oftalmološki kirurški postopki politetrafluoretilen