Avtor/Urednik		Zupan, S; Filipič, B; Eberl-Gregorič, E; Babič, M
Naslov		Piezoelectric immunosensors for detection of antibodies against Legionella pneumophila
Tip		članek
Vir		In: Abstract books of the 6th European congress on biotechnology; 1993 Jun 16 (vol 3). Firenze: European federation of biotechnology,
Vol. in št.		Letnik 3
Leto izdaje		1993
Obseg		str. WE115-6
Jezik		eng
Abstrakt		Different types of non-electrode biosensors were constructed to determine biologically active molecules, like antibodies. It has been repeatedly demonstrated that proteins which are firmly bound on a selective surface change the transducer's signal. Among different types of transducer the piezoelectric quartz crystals are of interest. It is of interest to detect antigen-antibody interactions performing the measurements similarly as in ELISA. Presented report describes the binding of Legionella pneumophila antigen onto the 10 MHz AT-cut piezocrystal, and subsequent direct detection of antibodies in rabbit's sera. The data from immunosensor's measurements were correlated with those from ELISA assay performed under the same conditions.
Deskriptorji		LEGIONELLA PNEUMOPHILA ANTIBODIES LEGIONNAIRES' DISEASE ANTIGENS RABBITS ANTIGEN-ANTIBODY REACTIONS CRYSTALLOGRAPHY ENZYME-LINKED IMMUNOSORBENT ASSAY TIME FACTORS SENSITIVITY AND SPECIFICITY HERPESVIRUS 1, HUMAN