Avtor/Urednik		Kores-Plesničar, Blanka
Naslov		Personalized treatment of schizophrenia in everyday clinical practice
Tip		članek
Vir		In: 2nd International Conference on Creative Psychopharmacotherapy, September 23-26, 2015, Dubrovnik Zagreb : Medicinska naklada
Vol. in št.		Letnik 27, št. 3
Leto izdaje		2015
Obseg		str. 314-318
Jezik		eng
Abstrakt		Each day clinical practice tries to follow the idea and principles of personalized medicine. Besides predicting an individual's sensibility or predis position for developing schizophrenia, pharmacogenetic and pharmacogenomic approaches attempt to define and acknowledge important indicators of clinical response to antipsychotics namely their efficacy and adverse effects. The main focus of our article were not facts regarding the role CYP450 liver enzymes have in this; our purpose is introducing other, new genetic and epigenetic factors which could introduce important biomarkers in diagnostics of the disease itself the efficacy and tolerance for antipsychotics. There is stil! a huge gap between gathering and collecting information and using them for the personalized treatment of schizophrenia. From the genetic point of view personalized treatment of schizophrenia is the field we need to focus on and successfully incorporate it our everyday clinical practice in the future.
Proste vsebinske oznake		schizophrenia antipsychotics pharmacogenetics sizofrenija antipsihotiki farmakogenetika