Avtor/Urednik		Feder, TJ; Weissmueller, G; Žekš, B; Sackmann, E
Naslov		Spreading of giant vesicles on moderately adhesive substrates by fingering: a reflection interference contrast microscopy study
Tip		članek
Vir		Phys Rev E
Vol. in št.		Letnik 51, št. 4
Leto izdaje		1995
Obseg		str. 3427-33
Jezik		eng
Abstrakt		The spreading of giant vesicles of neutral phospholipids on avidin-covered solid substrates is studied by reflection interference contrast microscopy. Contact formation, bilayer-substrate separation distances, and edge profiles are evaluated. The spreading occurs in two steps: advancement of lobes of average thickness = 70 nm by fingering, sometimes followed by thinning to = 30+-10 nm, determined by interfacial forces, and resulting in a pancakelike shape. The average advancement speed of the fingers appears constant at early times (= 0.2 microm/s) and slows down at a later stage. Locally, the bilayer advances stepwise owing to discontinuous water expulsion. The spreading is impeded by pinning centers resulting in fjord formation. The vesicle spreading is tentatively interpreted in terms of the classical theory of viscous fingering.
Deskriptorji		LIPID BILAYERS PHOSPHOLIPIDS MICROSCOPY, INTERFERENCE DIMYRISTOYLPHOSPHATIDYLCHOLINE PHOSPHATIDYLCHOLINES