Avtor/Urednik		Rupnik, Erik; Kariž, Stojan; Iglič, Črtomir; Zidarn, Mihaela; Košnik, Mitja
Naslov		Življenje ogrožajoči angioedem po zaviralcu angiotenzinove konvertaze - prikaz dveh primerov
Prevedeni naslov		Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor - two case reports
Tip		članek
Vol. in št.		Letnik 84, št. 12
Leto izdaje		2015
Obseg		str. 866-870
ISSN		1581-0224 - Zdravniški vestnik
Jezik		slv
Abstrakt		Background. Angioedema is a rare but potentially very serious complication of treatment with angiotensin converting enzyme inhibitors (ACEI). Angioedema is due to the accumulation of bradykinin, because angiotensin converting enzyme is the key enzyme for its degradation. Case reports. We present two patients with life-threatening angioedema while taking ACEI. Both patients had already had episodes of angioedema. Angioedema didn't respond to adrenaline. In both patients intubation was difficult. Conclusion. In the acute phase of angioedema due to ACEI it is necessary to protect the airways. Bradykinin receptor inhibitors shorten the duration of episodes of angioedema. In the long term it is essential to permanently avoid ACEI.
Proste vsebinske oznake		isolated angioedema angiotensin converting enzyme inhibitors bradykinin izoliran angioedem zaviralci angiotenzinove konvertaze bradikinin