Avtor/Urednik		Lainščak, Mitja; Coats, Andrew J.
Naslov		The PARADIGM of ARNI's: Assessing reasons for non-implementation in heart failure
Tip		članek
Vol. in št.		Letnik 212, št. 1 June
Leto izdaje		2016
Obseg		str. 187-189
ISSN		2352-9067 - International journal of cardiology
Jezik		eng
Abstrakt		Several trials have targeted neutral endopeptidase to demonstrate benefits for patients with heart failure. In the PARADIGM-HF trial, a combination of sacubitril and valsartan was superior to enalapril in reducing the risk of death and of hospitalization for heart failure. In this editorial we apply the trial to heart failure population at large to estimate what proportion of patients might actually be treated in daily practice.
Deskriptorji		Heart failure Endopeptidases Srčno popuščanje Endopeptidaze Drug therapy Therapeutic use Uporaba za zdravljenje